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DTSTART;TZID=America/Los_Angeles:20260927T130000
DTEND;TZID=America/Los_Angeles:20270627T150000
DTSTAMP:20260910T220505Z
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SUMMARY:Santa Cruz Pickwick Club presents: Christie Mysteries
DESCRIPTION:Over the coming year\, Dickens Universe readers and Pickwick Club members will meet for discussions focused on these novels and their lasting influence on the mystery genre. This year’s reading series brings together four landmark works of crime fiction: The Mystery of Edwin Drood by Charles Dickens (Penguin Classics\, 2002)\, The Murder of Roger Ackroyd by Agatha Christie (William Morrow\, 2021)\, The Murder at the Vicarage by Agatha Christie (William Morrow\, 2025)\, and The Pale Horse by Agatha Christie (William Morrow\, 2011). Join Dickens enthusiasts and Pickwick Club members on Zoom for a series of discussions about these beloved books. \nRegister via Zoom \nReading Schedule:  \n\nSept 27: The Murder of Roger Ackroyd\nOct 25: The Pale Horse\nNov 22: The Murder at the Vicarage\nDec 27: The Mystery of Edwin Drood\nJan 24: The Mystery of Edwin Drood\nFeb 28: The Mystery of Edwin Drood\nMar 28: The Mystery of Edwin Drood\nApr 25: TBD\nMay 23: TBD\nJun 27: TBD\n\nRecommended Edition: We recommend the Penguin Classics edition of the novels for its appendices and notes\, but other versions are fine. First-time readers should avoid the Introduction if they don’t want spoilers. Download the novels to read at Gutenburg.org or listen at LibriVox.org. \nThe Santa Cruz Pickwick (Book) Club\, a branch of the Dickens Fellowship\, is a community of local bookworms\, students\, and teachers who meet monthly to discuss a nineteenth-century novel. The Santa Cruz Public Libraries provide support for the reading group.
URL:https://live-events-ucsc.pantheonsite.io/event/santa-cruz-pickwick-club-presents-christie-mysteries/2026-09-27/
CATEGORIES:Lectures & Presentations
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20261015T000000
DTEND;TZID=America/Los_Angeles:20261205T235959
DTSTAMP:20260922T171843Z
CREATED:20260922T165047Z
LAST-MODIFIED:20260922T171843Z
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SUMMARY:Exhibition—The Audacity to Create\, works by BIPOC UC Santa Cruz alumni
DESCRIPTION:The Audacity to Create is an alumni exhibition showcasing the work of UC Santa Cruz Black\, Indigenous\, and People of Color (BIPOC) alumni Alejandra Chavez\, Jorge Gomez-Gonzalez \, Katie Dorame\, Seráb Serabia\, Aleya Caballero\, Edward Ramirez\, Josselyne Morales\, and Marceline Valentine. \nADMISSION \n\nAttend in person at the Mary Porter Sesnon Art Gallery at UC Santa Cruz\nFREE and open to the public.\nGallery hours: Tues.–Sat.\, noon–5:00 p.m.\nGallery accessibility and visitor information here.\n\nFULL SCHEDULE OF EVENTS \n\nOngoing exhibition: Thurs.\, Oct. 15–Sat.\, Dec. 5\, noon–5:00 p.m.\nReception: Sat.\, Oct. 17\, 2:00–4:30 p.m.\nArtist talk: Sat.\, Nov. 7\, 2:00–3:30 p.m.\n\nPARKING \n\nLots 124 & 125 are the closest parking lots to the Gallery.\nParking is by permit or Aims Mobile Pay (AMP).\nCore West parking structure and West Remote Lot 127 are free/no permit required on weekends.\nLearn more about parking at UCSC via Transportation & Parking Services (TAPS).\n\n### \nThis program is open to the general public consistent with state and federal law.
URL:https://live-events-ucsc.pantheonsite.io/event/exhibition-audacity/
LOCATION:Mary Porter Sesnon Art Gallery\, Baskin Service Road\, Santa Cruz\, CA\, 95064
CATEGORIES:Exhibits
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20261025T130000
DTEND;TZID=America/Los_Angeles:20270725T150000
DTSTAMP:20260910T220505Z
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SUMMARY:Santa Cruz Pickwick Club presents: Christie Mysteries
DESCRIPTION:Over the coming year\, Dickens Universe readers and Pickwick Club members will meet for discussions focused on these novels and their lasting influence on the mystery genre. This year’s reading series brings together four landmark works of crime fiction: The Mystery of Edwin Drood by Charles Dickens (Penguin Classics\, 2002)\, The Murder of Roger Ackroyd by Agatha Christie (William Morrow\, 2021)\, The Murder at the Vicarage by Agatha Christie (William Morrow\, 2025)\, and The Pale Horse by Agatha Christie (William Morrow\, 2011). Join Dickens enthusiasts and Pickwick Club members on Zoom for a series of discussions about these beloved books. \nRegister via Zoom \nReading Schedule:  \n\nSept 27: The Murder of Roger Ackroyd\nOct 25: The Pale Horse\nNov 22: The Murder at the Vicarage\nDec 27: The Mystery of Edwin Drood\nJan 24: The Mystery of Edwin Drood\nFeb 28: The Mystery of Edwin Drood\nMar 28: The Mystery of Edwin Drood\nApr 25: TBD\nMay 23: TBD\nJun 27: TBD\n\nRecommended Edition: We recommend the Penguin Classics edition of the novels for its appendices and notes\, but other versions are fine. First-time readers should avoid the Introduction if they don’t want spoilers. Download the novels to read at Gutenburg.org or listen at LibriVox.org. \nThe Santa Cruz Pickwick (Book) Club\, a branch of the Dickens Fellowship\, is a community of local bookworms\, students\, and teachers who meet monthly to discuss a nineteenth-century novel. The Santa Cruz Public Libraries provide support for the reading group.
URL:https://live-events-ucsc.pantheonsite.io/event/santa-cruz-pickwick-club-presents-christie-mysteries/2026-10-25/
CATEGORIES:Lectures & Presentations
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DTSTART;TZID=America/Los_Angeles:20261030T024000
DTEND;TZID=America/Los_Angeles:20261030T154500
DTSTAMP:20261027T201352Z
CREATED:20261027T201352Z
LAST-MODIFIED:20261027T201352Z
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SUMMARY:CSE Colloquium: Accelerated Diffusion Models
DESCRIPTION:Presenter: Julius Berner\, NVIDIA \nAbstract: Diffusion and flow models have driven major advances in image\, video\, and 3D content generation\, as well as in a wide range of scientific applications. As the field moves toward interactive applications—including real-time editing\, world models\, and embodied AI—low-latency generation is becoming essential. This talk will begin with an overview of techniques for accelerating diffusion and flow models\, then examine step-distillation methods in detail. We will cover both trajectory-based approaches\, such as knowledge distillation\, consistency models\, and flow maps\, and distribution-based approaches\, such as adversarial distillation and variational score distillation. We will illustrate these methods with practical examples using our open-source FastGen library. \nBio: Julius Berner is a Research Scientist at NVIDIA\, where he works on post-training of diffusion and flow models for real-time media generation and interactive world models. His broader research spans generative modeling\, deep learning\, and scientific applications. Prior to NVIDIA\, he was a postdoc at Caltech and completed his PhD sub auspiciis praesidentis at the University of Vienna\, alongside research internships at Meta and NVIDIA. \nHosted By: Professor Daniel Fremont and Professor Leilani Gilpin \nZoom: https://ucsc.zoom.us/j/95300285113?pwd=62tnEPUtRrsmbW7SHTavaRbaF2afSr.1
URL:https://live-events-ucsc.pantheonsite.io/event/cse-colloquium-accelerated-diffusion-models/
LOCATION:Engineering 2\, Engineering 2 1156 High Street\, Santa Cruz\, CA\, 95064
CATEGORIES:Lectures & Presentations,Seminars
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20261030T100000
DTEND;TZID=America/Los_Angeles:20261030T133000
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SUMMARY:Seymour Center Homeschool Day: Spectacular Science
DESCRIPTION:Calling all homeschool families! Join the Seymour Center on Friday\, October 30\, at 10 a.m. for a morning of hands-on science investigations\, aquarium feeds\, a scavenger hunt\, and lots more. \n• Enjoy hands-on science investigations\, crafts\, and a scavenger hunt. \n• Make an enormous whale skeleton appear in front of your eyes\, then walk inside it with our special virtual reality experience. \n• Touch live bat stars and crabs\, and learn about bone-eating zombie worms and hagfish. \n• Marvel at Ms. Blue\, a massive blue whale skeleton\, and discover how science and engineering innovations helped us restore this beloved Santa Cruz icon. \nAdmission fees apply. Special activities are included at no additional cost. \nRSVP here by October 15 to receive details and activities.
URL:https://live-events-ucsc.pantheonsite.io/event/seymour-center-homeschool-day-spectacular-science/
LOCATION:Seymour Marine Discovery Center\, 100 McAllister Way\, Santa Cruz\, CA\, 95060
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20261030T103000
DTEND;TZID=America/Los_Angeles:20261030T120000
DTSTAMP:20261029T172103Z
CREATED:20261009T184943Z
LAST-MODIFIED:20261029T172103Z
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SUMMARY:ECE Special Seminar: "Bilevel Optimization for Agentic AI: From Theory to Retrieval-augmented Agentic Reinforcement Learning"
DESCRIPTION:Presented by: Quan Xiao\, PhD Candidate @ Cornell University \nDescription: “Agentic AI systems combine large language models with system-level design choices such as post-training data selection\, retrieval\, tool use\, and memory management in augmented inference. Training these systems involves multiple coupled objectives beyond task success\, including safety\, retrieval quality\, and adaptation efficiency. Sequential tuning can cause catastrophic forgetting\, while direct objective mixing training can introduce unit mismatch and obscure credit assignments across components. \nIn this talk\, I will present bilevel optimization as a framework for jointly learning LLM parameters and agentic-system design variables. I will introduce an efficient first-order penalty formulation that replaces lower-level optimality with a merit constraint\, avoiding Hessian inverses and differentiation through full inner trajectories. By turning the bilevel problem into a penalized objective with analyzable structure\, this formulation enables landscape analysis that leads to global convergence guarantees. \nI will conclude with an application to bilevel retrieval optimization for tool-using agents\, where retrieval enables LLMs to access up-to-date information and manage external memory. In this setting\, landscape analysis also guides the design of memory-efficient variants of the penalty method tailored to the application. Experiments on multi-hop and medical question-answering tasks demonstrate the effectiveness of jointly optimizing retrieval and the LLM. Using only a 3B LLM backbone\, the proposed approach outperforms direct inference with GPT-5.6 Luna\, as well as methods based solely on agentic reinforcement learning or retrieval optimization.” \nBio: Quan Xiao (https://jenniferquanxiao.github.io) is a Ph.D. candidate in the Department of Electrical and Computer Engineering at Cornell University. She received her M.S. in Electrical Engineering from Rensselaer Polytechnic Institute in 2023\, and her B.S. in statistics from the University of Science and Technology of China in 2020. Her research focuses on the theoretical foundations of bilevel and multi-objective optimization\, as well as their applications to generative\, agentic AI and hardware-algorithm co-design. Her work has appeared in leading machine learning and signal processing venues\, including NeurIPS\, ICML\, and IEEE Transactions on Signal Processing\, with papers selected for oral and spotlight presentations. \nQuan has received several awards\, including the IEEE Signal Processing Society Scholarship in 2024 and the Belsky Award for Computational Sciences and Engineering in Rensselaer Polytechnic Institute in 2023. Her research has also received supports from industries\, including Google and Lambda Research. \n  \nHosted by: Professor Yu Zhang\, Electrical & Computer Engineering Department \nWhen: Friday\, October 30th from 10:30AM to 12:00PM \nLocation: Engineering 2\, Room 506 \n  \nZoom Details \nhttps://ucsc.zoom.us/j/98981141879?pwd=VakP9XwQb4UlYSAFeacq3axlAyry25.1\nMeeting ID: 989 8114 1879\nPasscode: 816427
URL:https://live-events-ucsc.pantheonsite.io/event/ece-special-seminar-bilevel-optimization-for-agentic-ai-from-theory-to-retrieval-augmented-agentic-reinforcement-learning/
LOCATION:Engineering 2\, Engineering 2 1156 High Street\, Santa Cruz\, CA\, 95064
CATEGORIES:Seminars
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20261030T110000
DTEND;TZID=America/Los_Angeles:20261030T120000
DTSTAMP:20261029T161133Z
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SUMMARY:Menendez\, J. (BMEB) - Resolving the variation and remodeling of human centromeres and telomeres with telomere-to-telomere genomes
DESCRIPTION:Centromeres and telomeres are essential for chromosome stability\, yet their highly repetitive sequences have historically limited study of their variation and dynamics. Centromeres direct kinetochore assembly on megabase-scale alpha-satellite (αSat) arrays\, while telomeres protect chromosome ends. Both vary extensively between individuals and across cell divisions\, developmental states\, and disease. Long-read sequencing and complete telomere-to-telomere (T2T) assemblies now make these regions accessible. Centromere identity is specified epigenetically by the histone H3 variant CENP-A\, which coincides with centromere dip regions (CDRs). CDRs are hypomethylated domains within active αSat arrays and can be detected from native long-read methylation. Telomere length also varies between chromosome ends. However\, subtelomeric variation makes it difficult to assign telomeric reads to a chromosome end without an individual-specific assembly. \nBuilding on haplotype-resolved near-T2T genomes from the Human Pangenome Reference Consortium (HPRC)\, the objective of this proposal is to develop long-read and pangenome-based tools that map kinetochore assembly sites and chromosome-end-specific telomeres. I will apply these tools across inheritance\, population variation\, cell-state transitions\, and cancer. In Aim 1\, I will use centrodip to identify CDRs from PacBio HiFi and ONT reads. I will track CDR stability across cell passaging and a three-generation pedigree\, and define CDR variation across the HPRC. In Aim 2\, I will develop pangenome-based tooling that assigns telomeric reads to chromosome ends with lr-giraffe. I will apply it to matched PBMCs\, LCLs\, and hiPSCs to trace changes in telomere length and telomere variant repeat (TVR) content across cell states. In Aim 3\, I will annotate kinetochores and telomeres in six matched tumor/normal cell line pairs from the CASTLE panel. From these\, I will define somatic centromeric and telomeric mutations and compare their variability to the baseline variation established in Aims 1 and 2. Together\, this work will define how kinetochore assembly sites vary and are inherited across the human population. It will also define how centromeres and telomeres are remodeled by cancer and cell state. These tools will extend pangenome-scale analysis into the genome’s most repetitive regions\, with implications for chromosomal instability\, cancer\, and aging. \nEvent Host: Julian Menendez\, PhD Student\, Biomolecular Engineering & Bioinformatics  \nAdvisor: Karen Miga \nZoom: https://ucsc.zoom.us/j/5047377540?pwd=Sb2mUlOcfQ5mX3T9TIDOMaeWvkfOR0.1&omn=92984500915 \nPasscode: 184739
URL:https://live-events-ucsc.pantheonsite.io/event/menendez-j-bmeb-resolving-the-variation-and-remodeling-of-human-centromeres-and-telomeres-with-telomere-to-telomere-genomes/
LOCATION:Biomedical Sciences Building\, 575 McLaughlin Drive
CATEGORIES:Ph.D. Presentations
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20261030T110000
DTEND;TZID=America/Los_Angeles:20261030T150000
DTSTAMP:20260921T222447Z
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SUMMARY:Produce Pop-Up
DESCRIPTION:Produce Pop-Up is a twice-weekly organic farmstand open to all members of the UC Santa Cruz community. The program is dedicated to increasing access to fresh\, healthy\, and affordable organic produce\, with offerings sourced from the UCSC Farm and other local organic growers. \nAcademic year hours and locations: Beginning Oct. 2 \n\nWednesdays: 11 a.m. – 3 p.m. at McHenry Library\nFridays: 11 a.m. – 3 p.m. at Science and Engineering Library\n\nHow does it work? \nJust stop by during open hours to browse and pick up fresh produce! Items are available at low or no cost to support student food access. \nStay updated on produce availability and locations by following Produce Pop-Up Instagram. For questions\, email ucscproducepopup@gmail.com or visit the Center for Agroecology website.
URL:https://live-events-ucsc.pantheonsite.io/event/produce-pop-up/2026-10-30/
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20261030T130000
DTEND;TZID=America/Los_Angeles:20261030T140000
DTSTAMP:20261021T162533Z
CREATED:20261021T162533Z
LAST-MODIFIED:20261021T162533Z
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SUMMARY:Asri\, M. (BMEB) - Genome Inference in the Pangenome Era
DESCRIPTION:Human genome references have provided unified coordinate systems for mapping genetic variation\, enabling numerous discoveries in genomics. However\, mapping to a single linear reference can be misleading or even impossible when a sample’s genome is highly divergent from the reference\, an issue known as reference bias. Recent advances in long-read sequencing technologies and computational techniques have made generating high-quality genome assemblies at scale more feasible than ever. This shift has paved the way for efforts such as the Human Pangenome Reference Consortium (HPRC)\, whose mission is to build a human pangenome reference that represents human genetic diversity and mitigates reference bias. In this dissertation\, I present methods I developed that contribute to building more accurate pangenome references and advancing their applications in variant calling\, ultimately enabling more accurate genome inference. \nFirst\, I introduce Secphase\, a tool for correcting read mappings with direct applications in fixing assembly errors. Secphase corrects mismapped Pacific Biosciences (PacBio) HiFi reads by leveraging long-range phasing information from Oxford Nanopore Technologies (ONT) data. As a core component of the PHARAOH pipeline\, Secphase was coupled with DeepPolisher\, a transformer-based polisher\, to polish 230 HPRC assemblies\, reducing errors by half. \nSecond\, I present HMM-Flagger\, a reference-free tool for detecting structural misassemblies based on the coverage of mapped long reads. It models read coverage using a hidden Markov model (HMM)\, enabling it to classify coverage anomalies as erroneous blocks\, false duplications\, or collapsed blocks. HMM-Flagger has been used extensively in the evaluation and selection of genome assemblies for the HPRC releases. \nFinally\, as an application of pangenomes\, I highlight work on extending DeepVariant to build a pangenome-aware variant caller by augmenting sample-specific input data with pangenome alignments. Using Element Biosciences reads\, pangenome-aware DeepVariant generated call sets with up to 46.5% fewer errors than existing methods. \nEvent Host: Mobin Asri\, PhD Candidate\, Biomolecular Engineering & Bioinformatics  \nAdvisor: Benedict Paten \nZoom: https://ucsc.zoom.us/j/91210219698?pwd=HA0b0by9HcKlKiBua7anVBZ7ZfSfJu.1 \nPasscode: 594980
URL:https://live-events-ucsc.pantheonsite.io/event/asri-m-bmeb-genome-inference-in-the-pangenome-era/
LOCATION:Engineering 2\, Engineering 2 1156 High Street\, Santa Cruz\, CA\, 95064
CATEGORIES:Ph.D. Presentations
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DTSTART;TZID=America/Los_Angeles:20261030T193000
DTEND;TZID=America/Los_Angeles:20261030T193000
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SUMMARY:Barnstorm Presents: The Flick\, by playwright Annie Baker
DESCRIPTION:Set in a failing movie theater in central Massachusetts\, three employees sweep up spilled popcorn and tend to the last remaining 35-mm film projector in the state. Their daily struggles and quiet heartbreaks in the search for connection remind audiences to hold on to authenticity in hard times in The Flick\, written by playwright Annie Baker and directed by UC Santa Cruz students Lina Valderrama and Felix Rae Whitehouse. \nABOUT BARNSTORM\nUC Santa Cruz students experiment with and create their own innovative theater and gain a sense of operating and creating art in the Barnstorm Theater Company\, a student-run theater arts production company established in 2004.\n—\nADVISORIES \n\nThe Flick contains mature themes and language including themes of sexual assault.\nShort moments of flashing light from a projector.\nLimited seating capacity.\nTicket holders not seated at least 10 minutes before the advertised start time may forfeit their ticket/seat and no refund will be issued.\nThe performance is estimated at 3 hours\, including a 15-minute intermission.\n\nADMISSION \n\nAttend in person at the Theater Arts B100 Studio Theater at UC Santa Cruz.\nAccessibility and visitor resources available here online.\nTickets issued here through Eventbrite.\nFollow the Dept. of Performance\, Play & Design on Eventbrite and Barnstorm on Eventbrite for notifications and updates.\nFREE for UCSC undergraduate students (ticket required).\nGeneral admission “Pay What You Like” options $5–20\nA limited number of tickets/seats may be available at the door\, even after online ticket sales end or reach full capacity.\nDoors are scheduled to open 30 minutes prior to event start time.\n\nFULL SCHEDULE OF EVENTS \n\nThu.\, Oct. 29\, 2026\, 7:30 p.m.\nFri.\, Oct. 30\, 2026\, 7:30 p.m.\nSat.\, Oct. 31\, 2026\, 2:00 p.m. matinee\nSun.\, Nov. 1\, 2026\, 7:30 p.m.\n\nPARKING \n\nArts Lot 126 is the closest parking lot to the event.\nParking via UCSC permit or Aims Mobile Pay (AMP).\nThe Core West Parking Structure (Lot 112) is free of charge on weekends.\nLearn more about parking at UCSC via Transportation & Parking Services (TAPS).
URL:https://live-events-ucsc.pantheonsite.io/event/barnstorm-presents-the-flick/2026-10-30/
LOCATION:Theater Arts B100 Studio Theater\, 453 Kerr Rd\, Santa Cruz\, CA\, 95064\, United States
CATEGORIES:Performances
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END:VEVENT
END:VCALENDAR